Puppies may become car sick during the first couple of trips. Consider taking another person along to hold your new puppy. Your passenger should wear a seat belt and open the window about 3" to 4" from the top. Constantly, but slowly, rub the underneath of the puppy's neck. This proves to be effective most of the time. Take a towel along just in case your puppy does get sick. Upon your arrival home, you can do any needed cleanup. Give your puppy about 45 minutes to an hour to settle down - his little tummy will do just fine.